摘要 |
<p>Cpds. (I) R' = H, aryl opt. subst. by (1-4C)alkyl, (1-4C) alkoxy, (1-4C)alkyl S-, NO2, CN or halogen, or a heterocyclic residue with 5 or 6 ring atoms, opt. subst. by Me, Et, or halogen. R2 and R3 = H or (1-3 C) alkyl R4 = H, CO2H or (2-4C) CO2alkyl R5 = (1-4C) alkoxy, PhCH2O, tetrahydropyranyloxy, NH2 or OH R6 = (1-4C)alkyl, (1-4C)alkoxy, (1-4C)alkylS-, NO2, (2-4C)alkenyl, (2-4C)alkenyloxy, halogen, or H. A = a (1-5C) satd. or unsatd. hydrocarbon residue opt. subst. by halogen, or Ph. m = 0 or 1 p = 0 or 1 n = 0-3. Antiinflammatories, analgesics, and antipyretics, of high activity and very low toxicity.</p> |