发明名称 NOVEL DERIVATIVES OF 1-DIPHENYLMETHYL PIPERAZINE,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 The invention relates to new 1-diphenylmethylpiperazinyl derivatives, characterised in that they correspond to the general formula I, and to their therapeutically acceptable salts, …<IMAGE>… in which … …  - R1 and R2, which may be the same or different, represent a hydrogen atom, a halogen, a lower alkyl radical, a hydroxyl radical, an alkoxy radical, an alkyl carboxylate radical, an aryl or substituted aryl radical, …  - n can have the values 2 to 4, …  - X, Y, Z and W, which may be the same or different, represent a nitrogen atom or a carbon atom linked to a hydrogen atom, a halogen or to another alkyl, aryl, carboxyalkyl, carboxyl, hydroxyl, alkylhydroxy, sulphonic and alkylsulphonic radical. … …<??>The invention also relates to the process for preparing the compounds and to their use for the manufacture of medicaments intended for the prophylaxis and treatment of various histamine-induced allergic diseases.
申请公布号 ZA9105838(B) 申请公布日期 1992.04.29
申请号 ZA19910005838 申请日期 1991.07.25
申请人 LABORATORIOS DEL DR. ESTEVE, S.A. 发明人 MARIA ROSA CUBERES-ALTISENT;JORDI FRIGOLA-CONSTANSA;JUAN PARES-COROMINAS
分类号 A61K31/495;A61P37/08;A61P43/00;C07D207/32;C07D207/325;C07D231/14;C07D231/16;C07D233/56;C07D249/08;C07D521/00 主分类号 A61K31/495
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