摘要 |
The invention relates to new 1-diphenylmethylpiperazinyl derivatives, characterised in that they correspond to the general formula I, and to their therapeutically acceptable salts, …<IMAGE>… in which … … - R1 and R2, which may be the same or different, represent a hydrogen atom, a halogen, a lower alkyl radical, a hydroxyl radical, an alkoxy radical, an alkyl carboxylate radical, an aryl or substituted aryl radical, … - n can have the values 2 to 4, … - X, Y, Z and W, which may be the same or different, represent a nitrogen atom or a carbon atom linked to a hydrogen atom, a halogen or to another alkyl, aryl, carboxyalkyl, carboxyl, hydroxyl, alkylhydroxy, sulphonic and alkylsulphonic radical. … …<??>The invention also relates to the process for preparing the compounds and to their use for the manufacture of medicaments intended for the prophylaxis and treatment of various histamine-induced allergic diseases. |