发明名称 |
PROCESSO PARA PRODUCAO DE N-ACETIL-PARA-AMINOFENOL |
摘要 |
N-acetyl-para-aminophenol is prepared by contacting 4-hydroxyacetophenone oxime with a Beckmann rearrangement catalyst in an alkyl alkanoate reaction solvent. An integrated process is disclosed wherein 4-hydroxyacetophenone is reacted with a hydroxylamine salt and a base to obtain 4-hydroxyacetophenone oxime, the oxime product is extracted from the resulting reaction mixture with a substantially water-immiscible solvent, and the mixture of oxime and substantially water-immiscible solvent is contacted with a Beckmann rearrangement catalyst to produce N-acetyl-para-aminophenol. Novel Beckmann rearrangement catalysts are used to limit by-product formation in the ester solvent. |
申请公布号 |
BR9103122(A) |
申请公布日期 |
1992.04.28 |
申请号 |
BR19919103122 |
申请日期 |
1991.07.22 |
申请人 |
HOECHST CELANESE CORPORATION |
发明人 |
JOHN R. FRITCH;O. STANLEY FRUEHEY;THEODORE HORLENKO;DANIEL A. AGUIL;CHARLES B. HILTON;PHILIP S. SNYDER;WILLIAM J. SEELIGER |
分类号 |
B01J31/02;B01J31/04;C07B61/00;C07C231/10;C07C231/24;C07C233/25 |
主分类号 |
B01J31/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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