摘要 |
DIAGNOSTIC PROBE FOR DIABETES TYPE I PREDISPOSITION An oligonucleotide probe for diagnosing predisposition or susceptibility to type I diabetes, capable of specifically hybridizing with the gene sequence or wherein A is adenine, C is cytosine, G is guanine, T is thymine, and R is thymine or uracil. The probe may include at least 15 sequential nucleotides selected from the sequence or . The probe may be labeled with a detectable marker, such as an enzyme or biotin, and may be supplied in a diagnostic kit in combination with: a substratum capable of adsorbing DNA or cells, a restriction enzyme, and/or a detergent. |