发明名称 Method of treating asthma using (S)-alpha-fluoromethyl histidine and esters thereof.
摘要 <p>(S)- alpha -fluoromethylhistidine, a potent, selective, mechanism-based inhibitor of mammalian histidine carboxylase, the enzyme responsible for biosynthesis of histamine in mammals, is useful in the treatment of asthma.</p>
申请公布号 EP0481675(A2) 申请公布日期 1992.04.22
申请号 EP19910309307 申请日期 1991.10.10
申请人 MERCK & CO. INC. 发明人 KOLLONITSCH, JANOS
分类号 A61K9/12;A61K31/415;A61P11/08;C07D233/64 主分类号 A61K9/12
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