发明名称 |
DNA ENCODING A GRF PRECURSOR |
摘要 |
DNA ENCODING A GRF PRECURSOR mRNAs encoding for GRF sequences are identified in a pancreas tumor and sequenced. From the sequence, it is learned that hpGRF is initially a portion of a longer precursor peptide that is subsequently processed into hpGRF. cDNA made from such mRNA is transformed into a host cell which produces a GRF precursor. In vitro or in vivo processing can be used to obtain GRF from the precursor. |
申请公布号 |
CA1299119(C) |
申请公布日期 |
1992.04.21 |
申请号 |
CA19840457226 |
申请日期 |
1984.06.22 |
申请人 |
SALK INSTITUTE FOR BIOLOGICAL STUDIES (THE) |
发明人 |
GUBLER, ULRICH A.;LING, NICHOLAS C. |
分类号 |
C12N15/09;C07H21/04;C07K14/00;C07K14/575;C07K14/60;C12N1/21;C12N15/00;C12P21/00;C12P21/02;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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