发明名称 |
Use of aryl- and heteroaryl piperazinyl carboxamides in the treatment of various central nervous system disorders |
摘要 |
There are disclosed the use of the compounds of the formula (I) <IMAGE> (I) wherein R1 is 1-adamantyl, 3-methyl-1-adamantyl, 3-noradamantyl, unsubstituted or substituted-2-indolyl, 3-indolyl, 2-benzofuranyl or 3-benzofuranyl wherein the substituents are selected from lower alkyl, lower alkoxy and halo; R2 is unsubstituted or substituted phenyl, benzyl, or pyrimidinyl wherein the substituents are selected from lower alkyl, lower alkoxy, trifluoromethyl and halo; R3 is H or lower alkyl of 1 to 3 carbon atoms; n is the integer 0 or 1; and m is the integer from 2 to 5 and the pharmaceutically acceptable salts thereof.
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申请公布号 |
US5106849(A) |
申请公布日期 |
1992.04.21 |
申请号 |
US19910689409 |
申请日期 |
1991.04.22 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
ABOU-GHARBIA, MAGID A.;YARDLEY, JOHN P.;CHILDERS, JR., WAYNE E.;MOYER, JOHN A. |
分类号 |
C07D209/42;C07D239/42;C07D295/13 |
主分类号 |
C07D209/42 |
代理机构 |
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主权项 |
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地址 |
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