| 摘要 |
Compounds of formula: <IMAGE> in which - R1 represents a hydrogen atom or an alkyl, alkoxycarbonyl or phenyl radical (optionally substituted by one or more substituents chosen from halogen atoms and alkyl, alkoxy, alkylthio, nitro and amino radicals), R2 represents a hydrogen atom or an alkyl radical optionally substituted by an alkoxycarbonyl radical, - R3 represents a phenyl radical substituted (by at least one dialkylamino radical) or a quinolyl radical, or alternatively - R2 and R3 form, together with the nitrogen atom to which they are attached, a heterocycle chosen from the following rings: piperidino substituted (by at least one alkoxycarbonyl or dialkylcarbamoyl radical), 1-perhydroquinolyl, 1,2,3,4-tetrahydroisoquinolyl, 8-azaspiro[4.5]decan-8-yl, 2- or 3-phenyl-1-pyrrolidinyl, 8-aza-1,4-dioxaspiro[4.5]decan-8-yl or 1-pyrrolidinyl, - R4 represents a phenyl radical (optionally substituted by one or more substituents chosen from halogen atoms and alkyl, alkoxy and alkylthio radicals), a naphthyl, indolyl, quinolyl or phenylamino radical (whose phenyl nucleus is optionally substituted by one or more substituents chosen from halogen atoms and alkyl, alkoxy, alkylthio, hydroxy and hydroxyalkyl radicals), their preparation and medicinal products containing them.
|
