| 摘要 |
This invention relates to compounds having pharmacological activity, processes for their preparation, compositions containing them and methods of treatment involving their use. In its broadest aspect, the invention is concerned with compounds, having general formula (I) in which R<1> represents an alkyl C1-18 group optionally substituted by an aryl group or hydroxy or a cycloalkyl C3-6 group, R<2> represents an alkyl C1-18 group optionally substituted by an aryl group, or R<2> represents a group -CH2-X-R4 wherein X represents O or S, and R4 represents hydrogen, an aryl group, or an alkyl or alkenyl C1-18 group optionally substituted by an aryl group, R<3> represents OH, alkoxy C1-6 or -NHR<31>, wherein R<31> represents hydrogen, alkyl C1-6, OH or alkoxy C1-6 optionally substituted by an aryl group, R<5> represents hydrogen, an aryl group or an alkyl or alkenyl C1-18 group optionally substituted by an aryl group, n represents 0, 1, 2 or 3, p represents 0, 1 or 2, q represents 0 or 1, Y represents -CHR<6>-, -CH=CH-, O or S, in which R<6> represents hydrogen, an aryl group or an alkyl or alkenyl C1-18 group optionally substituted by an aryl group, and pharmaceutically acceptable derivates thereof. |
