摘要 |
<p>Improved medical devices and instruments prepared by an improved method of producing hydrophilic, gamma-irradiation or electron beam-irradiation induced polymerized and chemically grafted coatings or plastic surfaces of articles adapted for contacting living tissue, the improvement comprising carrying out the graft polymerisation in an aqueous solution under specific combinations of the following conditions: 1) monomer concentration in the range of from about 0.1 % to about 50 % by weight; 2) total gamma or electron beam irradiation dose in the range of from about 0.001 to less than about 0.50 Mrad; and 3) gamma dose rate in the range of from about 10 to about 2500 rads/min or electron beam-irradiation dose rate in the range of from about 10 to about 108 rads/min.</p> |