PRIMATE ERYTHROCYTE BOUND MONOCLONAL ANTIBODY HETEROPOLYMERS

摘要

The application relates to the use of antibodies in therapy. Monoclonal antibody heteropolymers are described which comprise a monoclonal antibody specific for the CR1 receptor on primate red blood cells covalently linked to a second monoclonal antibody specific for an antigen to be cleared from the circulatory system. The monoclonal antibody heteropolymers may be injected directly into a patient's circulatory system. Alternatively, red blood cells removed from a patient or a suitable donor may be contacted with the monoclonal antibody heteropolymers and then administered to the patient.