| 发明名称 |
METHOD FOR PRODUCING TH-INDEPENDENT CYTOTOXIC T LYMPHOCYTES |
| 摘要 |
The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help. |
| 申请公布号 |
WO9205794(A1) |
申请公布日期 |
1992.04.16 |
| 申请号 |
WO1991US06921 |
申请日期 |
1991.09.24 |
| 申请人 |
IMMUNEX CORPORATION |
发明人 |
GREENBERG, PHILIP, D.;OVERELL, ROBERT, W. |
| 分类号 |
A61K35/14;C07K14/715;C12N5/0783;C12N5/10;C12N15/09;C12N15/12;C12N15/24;C12P21/02 |
主分类号 |
A61K35/14 |
| 代理机构 |
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代理人 |
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