发明名称 TETRAPEPTIDI PARZIALMENTE MODIFICATI E RETROINVERTITI, ANALOGHI DI FRAMMENTI DELLA PROTEINA C-REATTIVA.
摘要 PCT No. PCT/EP93/00825 Sec. 371 Date Sep. 27, 1994 Sec. 102(e) Date Sep. 27, 1994 PCT Filed Apr. 2, 1993 PCT Pub. No. WO93/21208 PCT Pub. Date Oct. 28, 1993.Retro-inverted tetrapeptides of formula I e side-chain of threonine; R1 is the side-chain of arginine, leucine or glutamine; and R2 is a hydrogen atom or a metabolically perishable acyl group; with the proviso that when R1 is the side-chain of arginine, R cannot be the side-chain of threonine; diastereo-isomeric forms and pharmacologically acceptable salts, esters and amides thereof. These compounds are useful as immuno-stimulating agents.
申请公布号 ITMI920939(D0) 申请公布日期 1992.04.16
申请号 IT1992MI00939 申请日期 1992.04.16
申请人 ITALFARMACO S.P.A. 发明人 VERDINI ANTONIO SILVIO;PINORI MASSIMO;CAPPELLETTI SILVANA;GAZERRO LAURA
分类号 A61K38/00;A61P9/00;C07K5/02;C07K5/033 主分类号 A61K38/00
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