摘要 |
A compound of general formula (I), wherein X is hydrogen, -CHCONH2 or -CH2CH2CONH2; each of R1, R2 and R3 is an L- alpha -amino acid, a delta -amino acid or an epsilon -amino acid; R4 is an L or D alpha -amino acid, a delta -amino acid or an epsilon -amino acid; and each of R5 to R11 is hydrogen or an L or D alpha -amino acid, a delta -amino acid or an epsilon -amino acid, or a pharmaceutically acceptable salt thereof. Methods of synthesis of peptides according to general formula (I), compositions containing the peptides, and uses of the peptides are also disclosed and claimed. |
申请人 |
MONASH UNIVERSITY;AUSTRALASIAN DRUG DEVELOPMENT LIMITED |
发明人 |
HEARN, MILTON, THOMAS, WILLIAM;NG, FRANK, MAN-WOON;ROBSON, VICTORIA, MARIE, JANE;O'DONOGHUE, MICHAEL, FRANCIS;RAE, IAN, DAVID |