发明名称 |
Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use |
摘要 |
Monoclonal antibodies capable of binding antigenic determinants within regions of the core proteins of the Human Immunodeficiency Virus and immortalized cell lines producing those monoclonal antibodies are provided. The monoclonal antibodies find use in a variety of ways, including HIV antigen detection in biological samples. Using these methods, individuals may be identified who are infected with HIV but who have not yet developed anti-HIV antibodies. The methods also find use in monitoring in vitro growth of HIV, and the efficacy of therapeutic agents and vaccines.
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申请公布号 |
US5104790(A) |
申请公布日期 |
1992.04.14 |
申请号 |
US19870105761 |
申请日期 |
1987.10.07 |
申请人 |
GENETIC SYSTEMS CORPORATION |
发明人 |
FLESHER, ALAN R.;SHRIVER, MARY K. |
分类号 |
A61K38/00;C07K14/16;C07K16/10;C12P21/08;C12Q1/70;G01N33/569 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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