发明名称 Reagents and method for therapeutic treatment of multiple sclerosis
摘要 The administration internally to humans of certain imidazol derivatives, especially N''-cyano-N-methyl-N'-[2[[(5-methyl-1H-imidazol-4-yl) methyl]thio]-ethyl]-guanidine (cimetidine) or salts thereof, is an effective therapeutic treatment for multiple sclerosis, both acute and chronic. The imidazole moiety is theorized to directly inhibit spread of the virus theorized to cause multiple sclerosis. Treatment of multiple sclerosis with metronidazole with one bolus dose on a frequency of once a day or less and with cimetidine on a frequency of twice per day has been found to be highly efficatious with minimal suppression of the patient's natural immune system and minimal long term peripheral nerve damage.
申请公布号 US5102902(A) 申请公布日期 1992.04.07
申请号 US19900517082 申请日期 1990.05.01
申请人 MERCER, JAMES B. 发明人 MERCER, JAMES B.
分类号 A61K31/415 主分类号 A61K31/415
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