| 摘要 |
<p>PURPOSE:To profitably produce the subject compound under a mild condition without using a mercury catalyst by adding an auric halide, auric halide acid or a metal salt thereof to the reaction system, when the subject compound is prepared from an alkine and an alcohol. CONSTITUTION:A compound of formula I (R<1>, R<2> are H, substituted or non- substituted alkyl, substituted or non-substituted aryl, group of formula II; (n) is an integer of 1-16) is reacted with an alcohol of formula: R<3>OH (R<3> is alkyl) in the presence of a compound of formula III or IV (M is Li, Na, K, H; X is halogen (l) is 3, 4; (m) is an integer of 0-10) to readily prepare the objective compound of formula V useful as an intermediate for medicines, agricultural chemicals, dyes, etc., in a good yield at a lower temperature and in a shorter time than by conventional methods. Since the method permits to prepare the objective compound under a neutral condition, compounds readily decomposed or causing by-reactions under acidic conditions can also be employed as the raw materials.</p> |
