AUTOMATIC CONTROL SYSTEM FOR IMPROVED ELECTROPHORESIS

摘要

61 PATENT Attorney Docket No. 2558-397 AUTOMATIC CONTROL SYSTEM FOR IMPROVED ELECTROPHORESIS A system for improving the electrophoretic separation of macromolecules with the aid of a computer is described. The system maintains a knowledge base derived from calibration data obtained by separating macromolecules, in particular DNA, of known size under a variety of planned conditions chosen to optimize separations. The user enters the smallest and largest DNA sizes to be resolved. From this information, the system automatically sets the optimal Voltage Gradient, Angle, Initial Switch Time, Final Switch Time, Forward Voltage Gradient, and Reverse Voltage Gradient parameters, thereby increasing the resolution of electrophoresis.