发明名称 |
EXPRESSION OF MACROPHAGE INDUCIBLE PROTEINS (MIPs) IN YEAST CELLS |
摘要 |
Methods for the expression of mammalian MIP-1 alpha and MIP-1 beta are disclosed. The methods generally comprise introducing into a yeast cell, a DNA molecule capable of directing the expression and if desired the secretion of either MIP-1 alpha or MIP-1 beta . Methods for expression of constructs encoding both MIP-1 alpha and MIP-1 beta are also described. The MIP molecules so produced are biologically active. |
申请公布号 |
WO9205198(A1) |
申请公布日期 |
1992.04.02 |
申请号 |
WO1991US06489 |
申请日期 |
1991.09.13 |
申请人 |
CHIRON CORPORATION |
发明人 |
TEKAMP-OLSON, PATRICIA;GALLEGOS, CAROL, ANN |
分类号 |
A61K38/00;A61P37/00;C07K14/52;C12N1/19;C12N15/09;C12P21/02;C12R1/865 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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