| 摘要 |
In accordance with the present invention, there is now provided a method for the diagnosis of amyloidosis, which comprises subjecting a protein sample such as serum, cerebrospinal fluid or brain tissues containing amyloid deposits obtained from a patient suspected of suffering from an amyloidosis related disease to measurement of the amount of ubiquitin in said sample, and comparing the resulting amount with the amount of ubiquitin in a normal healthy patient. In a second aspect of the present invention, there is provided a method for the diagnosis of Alzheimer's disease, which comprises subjecting a protein sample obtained from the brain extract or cerebrospinal fluid of a patient suspected of suffering from Alzheimer's disease to measurement of the amount of ubiquitin, and comparing the resulting amount with the amount of ubiquitin in a normal healthy patient.
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