| 摘要 |
Title compds. (I; X, Y = H, halogen, CF3, alkyl, alkoxy, alkylthio, alkylsulfonyl, alkylsulfiny1, NH2, NO2; Z = halogen, substituted NH2 or N-heterocycly1; m = 0, 1; n = 2-4) and their acid addn. salts were prepd. for use as analgesics, antidepressants and anticovulsants (ED50 0.3 - 7.6 mg/kg). Thus, 10,11-dihydro-10-hydrosydibenz≮bf≉oxepin reacted with Me2NCH2CH2SHHCl in the presence of BF3Et2O, followed by treatment with NaOH to give I(X,Y = H; Z = Me2N; m=0; n=2).
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