79 /AOR44 18156 TITLE OF THE INVENTION ANTIVIRAL AGENT An antiviral agent produced by Hypoxylon fragiforme and having the structure: is described. The product has high activity as an HIV protease enzyme inhibitor and is useful in the treatment of diseases in which control of HIV protease activity is desirable.
申请公布号
CA2052097(A1)
申请公布日期
1992.03.26
申请号
CA19912052097
申请日期
1991.09.24
申请人
BILLS, GERALD F.;HENSENS, OTTO D.;KOUPAL, LAWRENCE;LINGHAM, RUSSELL B.;ONDEYKA, JOHN G.;ZINK, DEBORAH L.
发明人
BILLS, GERALD F.;HENSENS, OTTO D.;KOUPAL, LAWRENCE;LINGHAM, RUSSELL B.;ONDEYKA, JOHN G.;ZINK, DEBORAH L.