发明名称 AMINO ACID DERIVATIVES
摘要 The compounds of the formula <IMAGE> in which A, B, X, Y, R<1>, R<2>, R<3>, R<4> and R<5> have the meaning given in Claim 1, in the form of optically pure diastereomers, diastereomer mixtures, diastereomeric racemates or mixtures of diastereomeric racemates and pharmaceutically utilisable salts thereof inhibit the action of the natural enzyme renin and can therefore be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be prepared by various processes known per se.
申请公布号 ZA9104808(B) 申请公布日期 1992.03.25
申请号 ZA19910004808 申请日期 1991.06.21
申请人 F. HOFFMANN-LA ROCHE A.G. 发明人 QUIRICO BRANCA;MARCEL MUELLER;HEINZ STADLER;WOLFGANG WOSTL;MARIE-PAULE HEITZ;WERNER NEIDHART;ERIC VIEIRA
分类号 A61K31/435;A61K31/495;A61K31/50;A61P9/00;A61P9/12;C07D263/06;C07D471/04;C07D487/04 主分类号 A61K31/435
代理机构 代理人
主权项
地址