MICROBIAL PREPARATION OF 13.BETA.-13-DEOXY-22,23-DIHYDRO AVERMECTIN-B1A/B1B A GLYCONE

摘要

18113 TITLE OF THE INVENTION MICROBIAL PREPARATION OF 13.beta.-13-DEOXY-22,23-DIHYDRO AVERMECTIN-Bla/Blb AGLYCONE The known compound, 13.beta.-13-deoxy-22,23-dihydro-avermectin -Bla/81b Aglycone is prepared microbiologically from cultures of the novel microorganisms (MA-6762, ATCC 55069, MA-6763 ATCC 55070) or the known microorganism Streptomyces lavendulae MA-6555 (ATCC 14159). The compound is prepared by the biotransformation of 13-deoxy-22,23-dihydro avermectin Bla/Blb aglycone which oxidizes the 13-position and epimerizes the 13-position hydroxy group.