发明名称 |
ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF AZABICYKLOOCTANCARBOXYLSYRER OG FARMACEUTISK ACCEPTABLE SALTE HERAF |
摘要 |
<p>Aza bicycloheptane carboxylic acid derivatives (I) in their racemic and optically active forms, are new (where R1 is lower alkyl; R2 is OH or lower alkoxy; R3 is OH or lower alkoxy; R4 = alkyl or phenyl alkyl of at most 8C atoms). Treatment of hypertension and cardiac insufficiency. The cpds. reduce or suppress carbocypolypeptideses and enkephalinases, and so inhibit the conversion of the decapeptide angiotensine I into the octapeptide angiotensine II. /0.</p> |
申请公布号 |
DK162444(C) |
申请公布日期 |
1992.03.23 |
申请号 |
DK19810004601 |
申请日期 |
1981.10.19 |
申请人 |
ADIR |
发明人 |
VINCENT, MICHEL;REMOND, GEORGES;LAUBIE, MICHEL |
分类号 |
C07D451/06;A61K31/435;A61K38/00;A61P9/00;A61P9/12;A61P43/00;C07D221/02;C07D221/22;C07D223/32;C07D453/06;C07K5/02;(IPC1-7):C07D453/06 |
主分类号 |
C07D451/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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