| 摘要 |
Two translucent patch-type administration devices (TAD) used by attachment to the skin, are new. Integration type TAD, comprises; (a) a solvent reservoir (2) of ionising solvent, the upper side forming an electrode (1) open to the outside; (b) a hydrophilic polymer drug reservoir (3) contg. the drug, forming the lower part; (c) a water-swellable polymer skin needle supporter (5) in which a number of skin stimulating needles (4) (skin needles) are vertically fixed; (d) a stacking-structural adhesive layer (6) around the supporter (5); and (e) a solvent inlet (7) in the upper central part. The TADs are for electrical admin. of insulin in an ionising solvent. The TAD avoids inconvenient other methods of admin. such as injection, and avoids disadvantages of prior art TADS which may degrade the protein or cause irritation.
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