| 摘要 |
<p>Modified antibodies are disclosed which have been modified by chemical conjugation with a heterobifunctional reagent, such as SPDP. The use of these modified antibodies in the preparation of compositions for the diagnosis and therapy of cancer and other mammalian disease is also disclosed. These diagnostic uses include immunoscintography. The modified antibodies can be further conjugated with labels or biologically active molecules for use in such diagnosis and therapy.</p> |
