| 摘要 |
Compounds of formula (II), wherein n is 0, 1 or 2, R1, R2, R3 and R4 are each separately selected from hydrogen, unsubstituted acyclic aliphatic hydrocarbon groups having a maximum of six carbon atoms and C1-6 alkyl groups substituted by a hydroxy group or by a C1-6 alkoxy group, or one of R1 and R2 and one of R3 and R4 is hydrogen and the others together form a trimethylene, tetramethylene or pentamethylene bridging group, R5 is hydrogen or an unsubstituted acyclic aliphatic hydrocarbon group having a maximum of six carbon atoms, and R6 is an acyclic aliphatic hydrocarbon group having a maximum of six carbon atoms or a group CH2R7 in which R7 is a C1-5 alkyl group substituted by a hydroxy group or by a C1-6 alkoxy group, or a salt thereof formed with a physiologically acceptable inorganic or organic acid, are of use in therapy, particularly as cardioprotective agents. |
