发明名称 |
2-acyloxy-4-morpholinyl anthracycline. |
摘要 |
<p>Anthracycline glycosides of formula 1: <CHEM> wherein R1 is hydrogen or methoxy group; R2 is hydrogen or hydroxy; both R3 and R4 represent hydrogen or one of R3 and R4 is hydroxy and the other of R3 and R4 a represents hydrogen; R5 represents hydrogen atom or an acyl residue - COX in which X is a C1-C8 linear or branched alkyl chain, an aryl, an aryl lower alkyl, or a 5- or 6-membered heteroaromatic group are anti-tumour agents.</p> |
申请公布号 |
EP0475071(A1) |
申请公布日期 |
1992.03.18 |
申请号 |
EP19910113170 |
申请日期 |
1991.08.06 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
FAIARDI, DANIELA;BARGIOTTI, ALBERTO;SUARATO, ANTONINO |
分类号 |
A61K31/704;A61K31/70;A61K31/7028;A61K31/7034;A61K31/7042;A61K31/7052;A61P35/00;C07H15/252;C07H19/24 |
主分类号 |
A61K31/704 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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