发明名称 |
Gene for human epidermal growth factor and synthesis and expression thereof |
摘要 |
A DNA having a base sequence coding for human epidermal growth factor has been synthesized in blocks, and cloned. Novel recombinant DNA transfer vectors containing said cloned DNA have been constructed. The codon usage of the sequence reflects the codon bias of yeast. The DNA sequence is useful for the large scale synthesis of human epidermal growth factor in yeast cells or microorganisms transformed by said recombinant DNA transfer vectors.
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申请公布号 |
US5096825(A) |
申请公布日期 |
1992.03.17 |
申请号 |
US19870004212 |
申请日期 |
1987.01.05 |
申请人 |
CHIRON CORPORATION |
发明人 |
BARR, PHILIP J.;MERRYWEATHER, JAMES P.;MULLENBACH, GUY T.;URDEA, MICKEY S.;VALENZUELA, PABLO |
分类号 |
C07K14/485;C12N15/18 |
主分类号 |
C07K14/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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