发明名称 |
NON-ANTIBACTERIAL TETRACYCLINE COMPOSITIONS POSSESSING ANTI-COLLAGENOLYTIC PROPERTIES AND METHODS OF PREPARING AND USING SAME |
摘要 |
Tetracyclines having substantially no effective antibiotic or antibacterial activity and possessing anti-collagen-destructive enzyme activity or anticollagenase activity and compositions containing the same have been found useful as anti-collagenolytic agents. Such tetracyclines and compositions containing the same are. useful in the treatment of periodontal diseases, corneal ulcers, bone deficiency disorders, rheumatoid arthritis diseases characterized by excessive collagen destruction. A special aspect of this invention involves the incorporation of such tetracyclines in animal feed compositions for improved animal nutrition, such as may be evidenced by increased weight gain. |
申请公布号 |
CA1297410(C) |
申请公布日期 |
1992.03.17 |
申请号 |
CA19860500004 |
申请日期 |
1986.01.21 |
申请人 |
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (THE) |
发明人 |
MCNAMARA, THOMAS F.;RAMAMURTHY, NUNGAVARAM S.;GOLUB, LORNE M. |
分类号 |
A23K1/165;A23K1/16;A23K1/17;A61K31/65;A61P1/02;A61P3/00;A61P43/00 |
主分类号 |
A23K1/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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