摘要 |
Diphenylurea derivatives of formula (I), wherein R<1> represents alkyl, X<1> represents oxygen, -OCH2- or -S(O)n-, wherein n is zero, 1 or 2, R<2> and R<3> each represents hydrogen, methyl or ethyl, R<4> represents alkyl, dimethylamino, -OR<6> or -S(O)mR<6>, wherein m is zero, 1 or 2 and R<6> represents alkyl optionally containing one or more carbon-carbon double bonds, and optionally interrupted by one or more hetero atoms, and R<5> represents -NR<7>R<8> or -OR<9>, wherein R<7> and R<8> each represents hydrogen or alkyl optionally containing one or more carbon-carbon double bonds, and optionally interrupted by one or more hetero atoms, and R<9> represents alkyl optionally containing one or more carbon-carbon double bonds, and optionally interrupted by one or more hetero atoms possess useful pharmacological properties. |