发明名称 |
PHOSPHOLIPID DERIVATIVES, THEIR PRODUCTION AND USE |
摘要 |
Phospholipid derivatives of the formula: wherein Rl is a higher alkyl, acylmethyl or alkylcarbamoyl group which may be substituted by cycloalkyl; R2 is a lower alkyl which may be substituted by carboxy, formyl or lower acyl, a carbamoyl or thiocarbamoyl group which is substituted by lower alkyl, or an acetoacetyl group; R3, R4 and R5 are independently hydrogen ox lower alkyl, or represents a cyclic ammonio group; and n represents an integer of 8 to 14, and salts thereof have antitumor activity and platelet activating factor inhibitory activity and are useful as antitumor agents. |
申请公布号 |
CA1297102(C) |
申请公布日期 |
1992.03.10 |
申请号 |
CA19860523911 |
申请日期 |
1986.11.27 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
INOUE, KEIZO;NOMURA, HIROAKI;OKUTANI, TETSUYA |
分类号 |
A61K31/685;A61P35/00;C07F9/10;C07F9/58 |
主分类号 |
A61K31/685 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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