发明名称 USE OF CARBOXYLIC ACID AMIDES FOR TREATING INFLAMMATIONS
摘要 RAN 4070/69 Compounds of the formula I wherein R1, R2, R3, R4 and R5 each independently represent hydrogen, alkyl, preferably lower -alkyl, or C3-7-cycloalkyl or two adjacent residues R1 to R5 represent an optionally lower-alkyl- -substituted 5-7-membered ring: X represents a residue -NR7-CO- or -CO-NR7-; R6 represents hydroxy, lower-alkoxy or -NR8R9; and R7, R8 and R9 represent hydrogen or lower-alkyl, and pharmaceutically usable salts of carboxylic acids of formula I can be used for the treatment of inflammatory and rheumatic diseases.
申请公布号 CA1297033(C) 申请公布日期 1992.03.10
申请号 CA19870549573 申请日期 1987.10.19
申请人 HOFFMANN-LA ROCHE(F.) & CO. AKTIENGESELLSCHAFT 发明人 KLAUS, MICHAEL
分类号 A61K31/195;A61K31/165;A61K31/19;A61K31/235;A61P29/00;C07C67/00;C07C231/00;C07C233/65;C07C233/81;C07C237/42 主分类号 A61K31/195
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