发明名称 MONOCLONAL ANTIBODIES REACTIVE WITH NORMAL AND ONCOGENIC FORMS OF THE RAS P21 PROTEIN
摘要 TITLE NN-O211 MONOCLONAL ANTIBODIES REACTIVE WITH NORMAL AND ONCOGENIC FORMS OF THE ras p21 PROTEIN Monoclonal antibodies reactive with normal an oncogenic forms of the ras p21 protein. The antibodies are secreted by hybridomas obtained by immunizing mice with the Ha ras p21 protein containing the arginine mutation at position 12 of the protein. The antibodies and immunoreactive fragments thereof of useful for detection, diagnosis, quantitation, staging and classification of normal and activated ras p21s in normal tissues, malignant and premalignant lesions.
申请公布号 CA1297048(C) 申请公布日期 1992.03.10
申请号 CA19880571431 申请日期 1988.07.07
申请人 DU PONT (E.I.) DE NEMOURS AND COMPANY 发明人 CARNEY, WALTER P.
分类号 C07K14/82;C07K16/32;C12N5/20 主分类号 C07K14/82
代理机构 代理人
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