发明名称 |
PRODRUGS OF CARBONIC ANHYDRASE INHIBITORS |
摘要 |
Prodrugs are prepared of the carbonic anhydrase inhibitors 2-benzothiazolesulfonamide, hydroxymethazolamide, and dichlorphenamide. The prodrugs link a water soluble compound to the pharmacologically active carbonic anhydrase inhibitor through an enzymatically or hydrolytically degradable bond.
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申请公布号 |
US5095026(A) |
申请公布日期 |
1992.03.10 |
申请号 |
US19890410982 |
申请日期 |
1989.09.22 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
SCHOENWALD, RONALD D.;BARFKNECHT, CHARLES F. |
分类号 |
C12N9/99;A61K31/18;A61K31/41;A61K31/425;A61K31/428;A61K31/433;A61K31/70;A61K31/7028;A61P27/02;A61P27/06;A61P43/00;C07D277/80;C07D285/135;C07H15/18;C07H15/203;C07H15/26;C07H17/00 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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