发明名称 SPIRO[CYCLOALKYLBENZENE-1,1'-(1',2',3',4'-TETRAHYDROISOQUINOLINES)] HAVING NEUROPROTECTIVE PROPERTIES
摘要 <p>Compounds of formula (I), in which R1 and R2, which may be the same or different, represent hydrogen or C1-6 alkyl, R3 and R4 independently represent one or more radicals selected from hydrogen, OH, NH2, NO2, halogen, C1-6 alkyl or C1-6 alkoxy and n is an integer from 1-2 inclusive, and pharmaceutically acceptable derivatives thereof are useful as pharmaceuticals; in particular, they possess N-methyl-(d)-aspartate (NMDA) blocking properties and are useful in the treatment and/or prevention of neurodegenerative conditions.</p>
申请公布号 WO1992003420(A1) 申请公布日期 1992.03.05
申请号 US1991005887 申请日期 1991.08.19
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