发明名称 |
Mono-N,N-dimethyl-4-aminopyridinium sn-glycerol-3-phosphate, production and use thereof in preparation of phosphatidic acids. |
摘要 |
<p>A process for preparing crystalline N,N-dialkyl-4-aminopyridinium salts from sn-glycerol-3-phosphate or an analogue thereof characterised in that it comprises: (a) reacting a free acid form of sn-glycerol-3-phosphate or an analogue thereof with an N,N-dialkyl-4-aminopyridine to form a salt solution; and (b) obtaining the N,N-dialkyl-4-aminopyridinium sn-glycerol-3-phosphate salt from the salt solution by precipitation with an organic solvent one or more times is disclosed. A process for the preparation of a phosphatidic acid is also disclosed.</p> |
申请公布号 |
EP0473435(A1) |
申请公布日期 |
1992.03.04 |
申请号 |
EP19910307922 |
申请日期 |
1991.08.29 |
申请人 |
GENZYME CORPORATION |
发明人 |
SCHENA, DAVID G.;DAVIS, JEFFREY |
分类号 |
C07D213/74;C07F9/09;C07F9/10 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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