Use of 2-(phenoxypropanolamino)ethoxyphenoxyacetic acid and its derivatives to inhibit gastrointestinal motility.

摘要

The use of a compound of the formula (I): <CHEM> wherein R is hydroxy or 2-methoxyethylamino or a pharmaceutically acceptable salt thereof, in stimulating the 'atypical' beta -adrenoceptors in the gastrointestinal tract and thereby inhibiting gastrointestinal motility. These compounds may be used for treating medical conditions wherein inhibition of gastrointestinal motility is thought to be of value, such as in the treatment of inflammatory bowel disease, irritable bowel syndrome (IBS), non specific diarrhoea and dumping syndrome.