摘要 |
PCT No. PCT/NL91/00148 Sec. 371 Date May 21, 1993 Sec. 102(e) Date May 21, 1993 PCT Filed Aug. 7, 1991 PCT Pub. No. WO92/02505 PCT Pub. Date Feb. 20, 1992.Process for the preparation of substituted pyridines by allowing 1-aza-1,3-butadienes to react, in the presence of a catalytic amount of secondary amine and acid, with an aldehyde or ketone, and new 1-aza-1,3-butadienes which are used in this process. Said pyridines can be obtained in high yield in a simple process with a short reaction time. The 1-aza-1,3-butadiene can, if so desired, be prepared in situ from an imine and an aldehyde. |