| 摘要 |
Novel pro-drugs to new and unnatural dipeptoids of .alpha.-substituted Trp-P he derivatives useful as agents in the treatment of obesity, hypersecretion of gastric acid in the gut, gastrin-dependent tumors , or as antipsychotics are disclosed. Further, the dipep- toids are antianxiety agents and antiulcer agents. They are agents useful fo r preventing the response to the withdrawal from chronic treatment or with use of nicotine, diazepam, alcohol, cocaine, caffeine, or opioids. The pro-drugs are also useful in treat- ing and/or preventing panic attacks. Also disclosed are pharmaceutical compositions and methods of treatment using the pro- drugs as well as processes for preparing them and novel intermediates useful in their preparation. An additional feature of the invention is the use of the subject pro-drug compounds in diagnostic compositions.
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