| 摘要 |
PURPOSE:To produce L-lysine by the fermentation method at a low cost, by using a microorganism, having enhanced superoxide dismutase activity, belonging to the genus Brevibacterium or Corynebacterium and capable of producing L-lysine. CONSTITUTION:A microorganism, belonging to the genus Brevibacterium or Corynebacterium and having the ability to produce L-lysine is subjected to variation treatment. A strain having resistance to superoxide dismutase production increaser, superoxide dismutase induction inhibitor, superoxide radical reaction accelerator or an oxidizing agent feeding an enzyme forming the superoxide is selected from the resultant variant strain. The resultant variant strain has enhanced superoxide dismutase activity and can be cultivated to collect L-lysine from the culture fluid readily at a low cost. |
