发明名称 CYCLIC PEPTIDE
摘要 NEW MATERIAL:7-membered cyclic peptide shown by formula I to formula III (Phe is phenylalanine; Leu is leucine; Ile is isoleucine; Ala is alanine; Thr is threonine; Gly is glycine; Pro is proline; Trp is tryptophan; Tyr is tyrosine; Ser is serine) obtained from citrus fruits and 8-membered cyclic peptide shown by formula IV (Glu is glutamine; Val is valine). USE:Having physiologically active action. For example, having activity to a circulatory system of animal. PREPARATION:Pericarp of citrus fruit or pericarp of unripe citrus fruit is extracted with hot water, the prepared extract is purified stepwise, a crude cyclic peptide is collected as a solution of an organic solvent, which is purified by gel filtration or silica gel chromatography to give a cyclic peptide.
申请公布号 JPH0446195(A) 申请公布日期 1992.02.17
申请号 JP19900148797 申请日期 1990.06.08
申请人 CHISSO CORP 发明人 MATSUBARA YOSHIHARU;SAWABE AKIYOSHI;INOI TAKESHI
分类号 A61K38/00;A61P9/00;C07K7/64;C07K14/415 主分类号 A61K38/00
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