摘要 |
NEW MATERIAL:7-membered cyclic peptide shown by formula I to formula III (Phe is phenylalanine; Leu is leucine; Ile is isoleucine; Ala is alanine; Thr is threonine; Gly is glycine; Pro is proline; Trp is tryptophan; Tyr is tyrosine; Ser is serine) obtained from citrus fruits and 8-membered cyclic peptide shown by formula IV (Glu is glutamine; Val is valine). USE:Having physiologically active action. For example, having activity to a circulatory system of animal. PREPARATION:Pericarp of citrus fruit or pericarp of unripe citrus fruit is extracted with hot water, the prepared extract is purified stepwise, a crude cyclic peptide is collected as a solution of an organic solvent, which is purified by gel filtration or silica gel chromatography to give a cyclic peptide. |