发明名称 |
(Benzhydryloxyethylpiperidyl)aliphatic acid derivatives and their use in the treatment of allergies and asthma. |
摘要 |
Compounds of formula (I): <CHEM> in which: R<1> and R<2> are independently alkyl, alkoxy, trifluoromethyl, nitro or halogen; A is an aliphatic hydrocarbon group having from 2 to 8 carbon atoms whose chain contains at least 2 carbon atoms in a linear chain between the piperidine group and -COOH, said group optionally being unsaturated; and m and n are independently 0, 1, 2 or 3; and pharmaceutically acceptable salts and esters thereof have been found to have valuable anti-histamine properties without the usual side effects of anti-histamines. Methods of preparing the compounds are also provided.
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申请公布号 |
EP0470686(A2) |
申请公布日期 |
1992.02.12 |
申请号 |
EP19910302141 |
申请日期 |
1991.03.13 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
FUKUMI, HIROSHI;SAKAMOTO, TOSHIAKI;SUGIYAMA, MITSUO;YAMAGUCHI, TAKESHI;IIZUKA, YOSHIO |
分类号 |
A61K31/445;A61K31/452;A61P11/00;A61P11/08;A61P37/08;A61P43/00;C07D211/34 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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