PRODUCTION OF HERPES SIMPLEX VIRAL PROTEINS

摘要

Methods and compositions are provided for the cloning and expression of Herpes Simplex Virus (HSV type 1 or type 2) glycoprotein (gD) gene in single-cell host organisms. Also described are methods for culturing these novel single-cell organisms to produce HSV-gene products. The HSV gD- related polypeptides produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against HSV-1 and HSV-2 infections.