MONOCLONAL ANTIBODY FOR USE IN DRUG RESISTANT CANCERS AND PRODUCTION THEREOF

摘要

Monoclonal antibodies are disclosed that may be produced by hybridomas obtained by fusing a mouse spleen cell immunized with an ADRIAMYCIN TM -resistant human tumor cell and a mouse myeloma cell and which inhibit selectively the growth of cancer cells possessing pleiotropic drug resistance or enhance their sensitivity to said drug.