| 发明名称 |
IMMUNE CELL REGULATION WITH SRC PTK SEQUESTERING AGENTS |
| 摘要 |
Signal propagation in MIRR-coupled immune cell signalling pathways is extinguished or curtailed by sequestering Src family enzymes indigenous to the cell. Signal-curtailing ligands which cross-link MIRR extracellular domains and stabilize intra-cellular Src/MIRR complexes are exemplary sequestering agents which function as immune cell antagonists.
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| 申请公布号 |
WO9949732(A1) |
申请公布日期 |
1999.10.07 |
| 申请号 |
WO1998US17200 |
申请日期 |
1998.08.26 |
| 申请人 |
THE UNIVERSITY OF NEW MEXICO |
发明人 |
OLIVER, JANET, M.;WILSON, BRIDGET, S.;ORTEGA, ENRIQUE |
| 分类号 |
A61K38/00;C07K16/28;G01N33/50;(IPC1-7):A01N61/00;A61K31/00;C07K5/00;C07K7/00;C07K16/00;C07K17/00;G01N33/53 |
主分类号 |
A61K38/00 |
| 代理机构 |
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