| 摘要 |
A method for obtaining, from a biological fluid, tissues or cells, a peptide which is different from fibroblast growth factors and has growth factor activity. Said method comprises: protein extraction, one or more scrubber column chromatography processes, and/or one or more affinity chromatography processes on a polysaccharide residue-carrying column. All steps are carried out at a pH close to neutral, and protein extraction is performed in a detergent-free medium, whereby a very high extraction yield can be obtained. The peptide thereby obtained can be used as a mitogenic, neurotrophic or angiogenic agent, or as a healing promoter agent.
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