SUSTAINED-RELEASE FORMULATIONS

摘要

Sustained-release formulations of a water soluble or highly water soluble drug comprising sufficient granules to provide a predetermined dose or number of doses. Each of the granules comprises said water soluble or highly water soluble drug and has a coating of a pharmaceutical wax or wax-like material over substantially its whole surface. The granules are optionally further provided with a coating of a polymer or other non-wax material deposited from an aqueous suspension or solution. A method for preparing the formulations is also provided.