发明名称 |
INSULIN RECEPTOR |
摘要 |
Insulin receptor is purified in accordance with this invention to a level sufficient to enable amino acid sequencing thereof. DNA encoding insulin receptor is provided, as well as methods for synthesizing insulin receptor or its mutant in heterologous host cells transformed with vectors containing such DNA. Knowledge of the amino acid sequence for insulin receptor enables the preparation of novel immunogenic conjugates and antibodies raised against such conjugates. Novel therapeutically useful forms of the insulin receptor and anti-receptor antibodies are described.
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申请公布号 |
CA1341149(C) |
申请公布日期 |
2000.12.05 |
申请号 |
CA19860501666 |
申请日期 |
1986.02.12 |
申请人 |
GENENTECH, INC. |
发明人 |
RAMACHANDRAN, JANAKIRAMAN;BELL, JOHN RICHARD;ULLRICH, AXEL |
分类号 |
C12N15/09;A61K35/74;A61K38/00;A61K38/28;A61K39/00;A61K39/395;A61K39/44;A61P3/08;C07H21/04;C07K14/005;C07K14/195;C07K14/72;C07K16/00;C07K16/20;C12N5/00;C12N15/00;C12P21/00;C12P21/02;C12R1/91;(IPC1-7):C12N15/17;C12N5/10;C07K16/28;C07K14/62;C12N15/63 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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